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Program

Please note that the symposium will be held at two different venues:

March 31, 2016: Neue Aula, Universität Heidelberg, Universitätsplatz, 69117 Heidelberg
April 1 – April 2, 2016: Lecture Hall, Medical Center, Department of Medicine, Im Neuenheimer Feld 410, 69120 Heidelberg

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Day 1
31 Mrz 2016
Day 2
01 Apr 2016
Day 3
02 Apr 2016
08:30 - 08:40
Neue Aula, Universität Heidelberg, Universitätsplatz, 69117 Heidelberg

Opening

Christoph Dahl, Managing Director, Baden-Württemberg Foundation and Wolfgang Herzog, Dean Faculty of Medicine, Heidelberg
08:40 - 09:05
Boukamp, Petra

The niche: A determinant for stem cell maintenance and function in normal skin and skin carcinomas

08:40 - 10:20

Session 1 – Stem Cells and Niche

Chairpersons: Alwin Krämer, Stefan Meuer
09:05 - 09:30
He, Xi Xi

Dynamic interaction between tumor initiating cells and immune response

09:30 - 09:55
Klein, Gerd

Molecular and biophysical characterization of the human hematopoietic stem cell niche

09:55 -10:20
Rudolph, Lenhard

Mechanisms and targets to improve function and genetic stability of hematopoietic stem cells at aging

10:20 - 10:50

Coffee break

10:50 - 12:50

Session 2 – Neuronal Stem Cells, Mitochondrial Damage

Chairpersons: Anna Wobus, Christof von Kalle
10:50 - 11:15
Ciccolini, Francesca

Quiescent stem cells in the adult mammalian brain

11:15 - 11:40
Rothfuss, Oliver

Akt dependent regulation of self renewal in pluripotent stem cells

11:40 - 12:05
Taylor, Verdon

Notch surprises in brain tumor formation and neural stem cell fate

12:05 - 12:50
Suda, Toshio

Key-note lecture

Controlling growth and maturation of blood stem cells
12:50 - 14:00

Lunch break

14:00 - 16:30

Session 3 – Hematopoietic Stem Cells and iPS

Chairpersons: Motomu Tanaka, Rupert Handgretinger
14:00 - 14:25
Scharffetter-Kochanek, Karin

Mesenchymal stem cells promote tissue repair

14:25 – 14:50
Glimm, Hanno

Functional and genetic heterogeneity in gastrointestinal cancers

14:50 – 15:15
Utikal, Jochen

Differentiation of induced pluripotent stem cells into cutaneous lineages

15:15 – 15:40
Lengerke, Claudia

The significance of selected stem cell proteines for the tumor biology of breast cancer

15:40 – 16:30
Keating, Armand

Key-note lecture

MSC for regenerative medicine, the way forward
08:30 – 09:15
Lecture hall, Medical Center, Department of Medicine, Im Neuenheimer Feld 410, 69120 Heidelberg
Schöler, Hans

Key-note lecture

Small organs, great potential: Recent advances in stem cell research
09:15 - 12:25

Session 4 – Molecular Fundaments of Stem Cells

Chairpersons: Peter Krammer, Konrad Beyreuther
09:15 – 09:35
Boutros, Michael

Reading and writing in the genome

09:35 – 09:55
Wittbrodt, Jochen

Stem cells in growth and regeneration of the retina

09:55 – 10:15
Niehrs, Christof

Not so canonical Wnt signaling

10:15 – 10:45

Coffee break

10:45 – 12:25

Session 5 – Stem Cells and Niche

Chairpersons: Hannah Monyer, Jürgen Hescheler
10:45 – 11:05
Lapidot, Tsvee

Metabolic regulation of blood and bone forming stem cells: The role of ROS and nitric oxide

11:05 – 11:25
Li, Linheng

Maintaining normal and targeting leukemia stem cells

11:25 – 11:45
Watt, Suzanne

Vascular niche and hematopoietic regeneration

11:45 – 12:05
Augustin, Hellmut

Angiocrine signaling during tissue homeostasis and in the bone marrow stem cell niche

12:05 – 12:25
Müller, Albrecht

Polycomb function in ESCs and HSCs

12:25 – 14:00

Lunch break

14:00 - 15:40

Session 6 – Clinical Transplantations – the Way Forward

Chairpersons: Rainer Haas, Klaus-Michael Debatin
14:00 – 14:20
Dreger, Peter

Novel trends in allogeneic stem cell transplantation

14:20 – 14:40
Liu, Dai-Hong

Unmanipulated haploidentical PBSCT for high-risk hematologic malignancies: Outcomes and feature of GVHD compared with matched related PBSCT

14:40 – 15:00
Heslop, Helen

Virus specific T-cells – moving to standard of care

15:00 – 15:20
Kröger, Nicolaus

Targeting MRD post transplant

15:20 – 15:40
Ball, Ted

Checkpoint inhibition for treatment of relapse after allogeneic stem cell transplantation

15:40 – 16:00

Coffee break

16:00 – 17:45

Session 7 – Clinical Transplantations – becoming obsolete?

Chairpersons: Bernd Dörken, Wolf-Karsten Hofmann
16:00 – 16:20
Hehlmann, Rüdiger

Cure of CML: Are we there yet?

16:20 – 16:40
Pfreundschuh, Michael

Stem cell transplantation in aggressive lymphomas: do we still need it?

16:40 – 17:00
Döhner, Hartmut

Genetics for guiding patient care in AML

17:00 – 17:45
Champlin, Richard

Key-note lecture

Advances with alternative donors: now everyone can get a transplant
08:30 – 09:15
Lecture hall, Medical Center, Department of Medicine, Im Neuenheimer Feld 410, 69120 Heidelberg
Franke, Werner

Key-note lecture

Wild and at random: Spontaneous and cumulative syntheses of epithelial molecules in various hematopoietic cells
09:15 – 10:35

Session 8 – Aging and Disorders of Stem Cells

Chairpersons: Jeroen Krijgsveld , Harald Klüter
09:15 – 09:35
Gavin, Anne-Claude

Omics profiling of HSC niche

09:35 – 09:55
Wagner, Wolfgang

How to keep your stem cells young – DNA methylation changes in aging

09:55 – 10:15
Lohmann, Jan

Control of stem cell identity: Lessons from plants

10:15 – 10:35
Trumpp, Andreas

Molecular and cellular control of normal and leukemic stem cells

10:35 – 11:00

Coffee break

11:00 – 12:00

Session 9 – Clinical Applications

Chairpersons: Hanns-Martin Lorenz, Konrad Kohler
11:00 – 11:20
van Laar, Jakob

Stem cell therapy in autoimmune disease – the facts

11:20 – 11:40
Andreeff, Michael

Leukemia stem cells

11:40 – 12:00
Goldschmidt, Hartmut

Role of autologous transplantation in pursuit of a cure

12:00 – 13:45

Session 10 – Evolution of Cellular Immunotherapy

Chairpersons: Michael Schmitt, Eric Rosenbaum
12:00 – 12:20
Kolb, Hans-Jochem

Evolution of cellular immunotherapy after the first DLI

12:20 – 12:40
Ehninger, Gerhard

Engaging T-cells with leukemia

12:40 – 13:00
Cichutek, Klaus

Stem cell based medicinal products – hopes and reality

13:00 – 13:45
Brenner, Malcolm

Key-note lecture

Driving CAR-T cells beyond B-cell Malignancy
13:45 – 14:45

Lunch break